Does BMA mean n-butyl methacrylate or isobutyl methacrylate?

In most commercial usage the bare abbreviation means the normal isomer, n-butyl methacrylate, CAS 97-88-1. The branched isomer, isobutyl methacrylate, is a different substance with its own identifiers and a different contribution to copolymer hardness, and the tertiary isomer is different again. Because all three are abbreviated loosely in day-to-day correspondence, an order written as BMA alone is ambiguous. Write the full chemical name and the CAS number on every enquiry, purchase order and goods-inwards record.

Why must the monomer not be blanketed with pure nitrogen?

Because the stabiliser used in commercial methacrylate monomers requires dissolved oxygen to function. It intercepts radicals by a mechanism that consumes oxygen, so a drum stripped of oxygen contains an inhibitor that is chemically present and functionally absent. The correct headspace is air, or air diluted with nitrogen to a specified oxygen content, never an inert blanket. This is one of the very few cases in a chemical store where displacing oxygen makes a material more dangerous rather than less, and it catches people whose instinct is trained on flammable solvents.

How should inhibitor content be read on a certificate?

As a starting condition rather than a permanent property. The certificate reports the inhibitor level at release; that level falls in storage as the stabiliser does its job, and it falls faster in warm conditions, in light and in the presence of contamination. A long-stored drum can meet its original certificate on every other line while having very little inhibitor left. Where storage has been long or uncertain, retest the inhibitor level before charging a reactor rather than relying on the release figure.

What is popcorn polymerisation and why does it matter here?

It is a self-propagating, expanding polymer growth that forms in dead legs, vapour spaces, valve bonnets and residues where inhibitor cannot reach. Once seeded it continues under conditions that would not start a normal polymerisation, and it grows mechanically enough to jam valves and distort equipment. The controls are housekeeping controls: no unswept dead legs, no long-standing residues, no lines left full between campaigns, and clean vessels before refilling. It is not a reason to avoid methacrylate monomers, but it is a reason to design the pipework as if the monomer were reactive, because it is.

How does the butyl ester change a copolymer compared with the methyl one?

The four-carbon ester side chain is flexible and bulky, so it loosens chain packing and lowers the temperature at which the polymer softens. Against the methyl ester it gives a softer, more flexible and more extensible polymer, better adhesion and easier film formation, at the cost of hardness and block resistance. Against the corresponding acrylate it gives a harder polymer with the weathering advantage of the methacrylate backbone. Formulators use it as the soft component of an all-methacrylate system, which keeps the durability while tuning flexibility.

L-Leucine is a chemical compound registered under CAS number 61-90-5. Molecular formula: C6H13NO2. Molar mass: 131.17 g/mol. IUPAC: (2S)-2-amino-4-methylpentanoic acid.

What is the CAS number of L-Leucine?

The CAS number of L-Leucine is 61-90-5 — a unique Chemical Abstracts Service (CAS) identifier.

What is the molecular formula of L-Leucine?

Molecular formula: C6H13NO2. Molar mass: 131.17 g/mol. logP (XLogP3): -1.5. PSA: 63.3 Å².

Where can I buy L-Leucine?

L-Leucine is available in our shop. View the product: https://epchems.online/products/l-leucine/

Where does the chemical data for L-Leucine come from?

Chemical data for L-Leucine comes from authoritative sources: PubChem (NIH), ChEMBL (EBI). PubChem CID: 6106. Compliant with the CLP Regulation (EC 1272/2008), available under the CC-BY 4.0 licence.

L-Leucine

CAS 61-90-5 · C₆H₁₃NO₂ · MW 131.17 g/mol

About L-Leucine

L-Leucine is a chemical compound registered under number CAS 61-90-5, with the molecular formula C₆H₁₃NO₂, and a molar mass of 131.17 g/mol.

The molecule contains 22 atoms connected by 21 chemical bonds. The full systematic IUPAC name of this compound is (2S)-2-amino-4-methylpentanoic acid. The interactive 3D model above lets you view the spatial arrangement of the atoms — you can rotate it with the mouse, zoom with the scroll wheel, and switch between skeletal / Ball & Stick / Space Fill visualization modes.

In terms of physicochemical properties, the partition coefficient logP = -1.5 (negative value, a hydrophilic compound), polar surface area PSA = 63.3 Å², 2 donors and 3 hydrogen bond acceptors. These parameters are key when assessing bioavailability and interaction with biomolecules.

Chemical data for this compound comes from PubChem (NIH NLM NCBI), one of the world's largest chemical databases. All information is updated automatically and enriched with GHS hazard statement translations compliant with the CLP Regulation (EC 1272/2008). The widget above may be used for educational, research and commercial purposes.

Physicochemical properties

Wzór sumaryczny	C₆H₁₃NO₂
Masa molowa	131.17 g/mol
IUPAC	(2S)-2-amino-4-methylpentanoic acid
SMILES	`CC(C)C[C@@H](C(=O)O)N`
InChIKey	`ROHFNLRQFUQHCH-YFKPBYRVSA-N`
logP (XLogP3)	-1.5
PSA	63.3 Å²
HBD / HBA	2 / 3
PubChem CID	CID 6106 ↗

Scientific literature

Literatura naukowa

7 artykułów · 4 open access · Źródła: PubMed, OpenAlex, Semantic Scholar

📈 Timeline publikacji (7 artykułów)

Wysokość słupka = liczba artykułów w roku. Hover dla szczegółów.

Conformation of Peptides Containing a Chiral -Ethylated ,-Disubstituted -Amino Acid: (S)--Ethylleucine (=(2S)-2-Amino-2-ethyl-4-methylpentanoic Acid) within Sequences of Dimethylglycine and Diethylglycine Residues

Makoto Oba, Masakazu Tanaka, Masaaki Kurihara et al. (2002) · Helvetica Chimica Acta

Cytowania: 38$ PaywallDOI ↗

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Acetyl-DL-leucine in two individuals with REM sleep behavior disorder improves symptoms, reverses loss of striatal dopamine-transporter binding and stabilizes pathological metabolic brain pattern-case reports.

Oertel WH, Janzen A, Henrich MT et al. (2024) · Nature communications

Open AccessDOI ↗PubMed ↗PDF ↗

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Pyruvate metabolism enzyme DLAT promotes tumorigenesis by suppressing leucine catabolism.

Wang N, Lu S, Cao Z et al. (2025) · Cell metabolism

Open AccessDOI ↗PubMed ↗PDF ↗

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HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity.

Dobersch S, Yamamoto N, Schutter A et al. (2025) · Nature communications

Open AccessDOI ↗PubMed ↗PDF ↗

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Chemotherapeutic agents and leucine deprivation induce codon-biased aberrant protein production in cancer.

Kochavi A, Nagel R, Körner PR et al. (2024) · Nucleic acids research

Open AccessDOI ↗PubMed ↗PDF ↗

Modified Xiaoyaosan rescues depression-like behavior via remodeling gut microbiota and leucine metabolism.

Zhao Y, Wang Q, Wu Z et al. (2025) · Phytomedicine : international journal of phytotherapy and phytopharmacology

$ PaywallDOI ↗PubMed ↗

BCKDK accelerates the progression of diabetic kidney disease by regulating leucine-mediated metabolic remodelling in renal tubular cells.

Shi C, Wang X, Qin S et al. (2025) · Diabetologia

$ PaywallDOI ↗PubMed ↗

Dane z PubMed (NIH NLM), OpenAlex (CC0), Semantic Scholar (AI2). AI Summary wygenerowane przez Semantic Scholar TLDR. Artykuły z ikoną wymagają płatnego dostępu.

Synonyms

L-leucine · leucine · 61-90-5 · (S)-2-Amino-4-methylpentanoic acid · (S)-Leucine · (2S)-2-amino-4-methylpentanoic acid · (S)-(+)-Leucine · Leucin · (S)-2-Amino-4-methylvaleric acid · L-alpha-Aminoisocaproic acid · LEUCINE, L- · Leucinum · Leucina · FEMA No. 3297 · (2S)-alpha-leucine

Data sources

📊 PubChem CID 6106 — NIH
🔬 NIST WebBook — spektroskopia
🌐 Wikidata
💊 ChEMBL — bioaktywność

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